The similarity of MDA and MDMA pharmacokinetics suggests that the greater duration of MDA effects is due to pharmacodynamics rather than pharmacokinetics. MDA The effects are more stimulating (excitement and hallucinations) and more long-lasting (about ten hours). There was considerable between-subject variation in MDA/HMA ratios. The main difference from MDMA is that 'the special, magic effect and the affective transfer seem to be absent'. Cmax and AUC 0-∞ for MDA were 229 ± 39 (mean ± SD) and 3636 ± 958 µg/L for MDA and 92 ± ± 741 µg/L for the metabolite 4-hydroxy-3-methoxyamphetamine (HMA). MDA self-report effects lasted longer than those of MDMA, with MDA effects remaining elevated at 8 h while MDMA effects resolved by 6 h. MDA self-report effects shared features with MDMA as well as with classical psychedelics. methylenedioxyamphetamine (MDA) and MDMA, a combination of MDA and methamphetamine or a combination of MDMA and methamphetamine). MDA induced robust increases in heart rate and blood pressure and increased cortisol and prolactin to a similar degree as MDMA. Common (small or sensitive people) 60 - 90 mg. Total duration is around 8 hours as opposed to MDMA's 5ish hours.
Sort of like taking MDMA and amphetamine at the same time. It has that feeling of content euphoria with a sense of love that MDMA has (to a slightly lesser extent) but with more physical stimulation than pure MDMA. higher dosage you can experience eye wiggles ( eyes wobbling (awesome feeling IMO). MDA is a longer lasting, more stimulating, and more visual drug. While peaking you shouldn't have any visual distortions/colour changes/ pattern emerging etc. You will feel relaxed, super mellow until you are going to hit your peak. We conducted a within-subjects, double-blind, placebo-controlled study of 1.4 mg/kg oral racemic MDA and compared results to those from our prior similar studies with 1.5 mg/kg oral racemic MDMA. Erowids current view is that the required dose of MDA vs MDMA are very similar, but result in slightly different effects (MDA is more physically stimulating while MDMA is more empathogenic at the same dose). MDMA : come up wise will be quicker than MDA. Yet the first known drug with such properties, 3,4-Methylenedioxyamphetamine (MDA), remains poorly studied and its pharmacokinetics in humans are unknown. Understanding their mechanisms can benefit from clinical experiments with related drugs. Anyone with an opinion on this topic PLease help.Zenx. Ive been searching for the negative effects of MDA with no luck. Mdp2p from piperonal.Entactogens such as 3,4-Methylenedioxymethamphetamine (MDMA, “molly”, “ecstasy”) appear to have unusual, potentially therapeutic, emotional effects. Ive recently taken some MDA pills (or at least I though they were MDA) and I've tripped harder than with the shitty 'MDMA' pills Ive tried lately.